Methotrax 10 is used for rheumatoid arthritis and severe psoriasis, preventing further joint damage and controlling skin cell overgrowth.
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Neoplastic Diseases:
Rheumatoid Arthritis:
Psoriasis:
Caution is advised when consuming alcohol with Methotrax 10 mg. Consult your doctor.
Methotrax 10 is an immunosuppressant, decreasing immune system activity. In psoriasis, it slows rapid skin cell growth.
Abdominal pain, Indigestion, Loss of appetite, Nausea, Vomiting, Tiredness, Mouth sore.
Burkitt's lymphoma, Choriocarcinoma, Mycosis fungoides, Crohn's disease, Psoriasis, Osteosarcoma, Breast cancer, Acute lymphoblastic leukaemia, Rheumatoid arthritis.
Methotrax 10 mg inhibits dihydrofolic acid reductase, interfering with DNA synthesis, repair, and cellular replication. It impairs malignant growth in actively proliferating tissues, more sensitive in malignant cells.
Neoplastic Diseases-Choriocarcinoma and similar trophoblastic diseases:
Acute Lymphoblastic Leukemia:
Lymphoma Burkitt's tumor:
Lymphosarcoma Stage III:
Mycosis fungicides:
Breast Cancer:
Head and Neck Cancer:
Adult Rheumatoid Arthritis:
Polyarticular-Course Juvenile Rheumatoid Arthritis:
Psoriasis:
Administration of Methotrax 10 mg:
Pregnancy category X. Contraindicated in pregnant and nursing women.
Leucovorin is indicated to diminish the toxicity and counteract inadvertent overdosages. Administer promptly.
Store at a temperature not exceeding 30°C in a dry place. Protect from light & moisture.
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